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Table 4 Percentage of simulated data sets where SRR was estimated as 0 (% ρ=0 ) and the bias of the corresponding SCR estimates taken as the percentage in relation to the true SCR

From: Sample size determination for estimating antibody seroconversion rate under stable malaria transmission intensity

Population

Sample size

SCR = 0.0036

SCR = 0.0108

% ρ=0

Bias (%)

% ρ=0

Bias (%)

Africa

250

28.6

−25.7

16.0

−26.1

 

500

21.9

−25.3

8.4

−26.6

 

1,000

13.1

−25.6

2.0

−25.6

 

2,500

3.7

−25.2

0.1

−26.4

 

5,000

0.6

−24.4

0.0

N/A

 

10,000

<0.1

−22.4

0.0

N/A

Elsewhere

250

27.0

−29.6

14.6

−30.5

 

500

20.1

−29.4

6.1

−30.2

 

1,000

11.2

−29.2

1.5

−30.7

 

2,500

3.0

−28.6

<0.1

−32.2

 

5,000

0.4

−28.8

0.0

N/A

 

10,000

0.0

N/A

0.0

N/A

  1. Bias was defined as the difference between the mean of the corresponding estimates and the true value of SCR. The true SRR that generated the data sets was fixed at 0.017.