Robust, reproducible, industrialized, standard membrane feeding assay for assessing the transmission blocking activity of vaccines and drugs against Plasmodium falciparum

Table 3 Results of models fit to assess different functional forms of K, the overdispersion parameter [16,31]

Model	Functional form	Log likelihood	AIC
Linear	k(M) = αM + ε	- 3204.317	6412.633
Power	k(M) = αM ^β + ε	- 3203.071	6412.142
Hyperbolic	\( k(M)=\frac{\alpha M}{1+\gamma M}+\varepsilon \)	- 3202.466	6410.931
Sigmoid	\( k(M)=\frac{\alpha {M}^{\beta }}{1+\gamma {M}^{\beta }}+\varepsilon \)	- 3202.357	6412.714

While all models fit the data similarly, the hyperbolic model was chosen as the final model based on its lowest Akaike’s information criterion (AIC).

ISSN: 1475-2875