Table 3 Prevalence of the T(−413)A and G(−1135)A alleles and genotypes
T(−413)A Alleles and genotypes N (%) | Controls (n=281) | Uncomplicated malaria (n=95) | Severe anaemia (n=61) | Cerebral malaria (n=119) | |
|---|---|---|---|---|---|
Alleles | A | 175 (31.1) | 56 (29.5) | 35 (28.7) | 70 (29.4) |
T | 387 (68.9) | 134 (70.5) | 87 (71.3) | 168 (70.6) | |
Genotypes | A/A | 26 (9.3) | 11 (11.6) | 5 (8.2) | 12 (10.1) |
A/T | 123 (43.8) | 34 (35.8) | 25 (41.0) | 46 (38.7) | |
T/T | 132 (47.0) | 50 (52.6) | 31 (50.8) | 61 (51.3) | |
G(−1135)A Alleles and genotypes N (%) | Controls (n=238) | Uncomplicated malaria (n=78) | Severe anaemia (n=55) | Cerebral malaria (n=107) | |
Alleles | G | 397 (83.4) | 123 (78.9) | 91 (82.7) | 179 (83.6) |
A | 79 (16.6) | 33 (21.2) | 19 (17.3) | 35 (16.4) | |
Genotypes | G/G | 179 (75.2) | 57 (73.1) | 42 (76.4) | 81 (75.7) |
G/A | 39 (16.4) | 9 (11.5) | 7 (12.7) | 17 (15.9) | |
A/A | 20 (8.4) | 12 (15.4) | 6 (10.9) | 9 (8.4) | |