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Table 3 Comparison of degree of precision in parasite index by measured and assumed total leucocyte counts among Plasmodium vivax patients of five primary health centres

From: Surmised total leucocyte counts miscalculate the parasite index of Plasmodium vivax malaria patients of tertiary and primary care settings in South-Western India

Assumed TLC

Underestimation (%)

Precision (%)

Overestimation (%)

Parasite index by measured TLC [median (IQR), 1,520 (504, 3,544)]

Z - score*

p-value*

4,000 cell/μL

0

99.2

0.8

1,180 (365, 3,185)

−4.2

<0.001

4,500 cell/μL

0

98.4

1.6

1,328 (411, 3,583)

−2.0

0.04

5,000 cell/μL

0

96.9

3.1

1,475 (456, 3,981)

−0.6

0.5

5,500 cell/μL

0

95.3

4.7

1,623 (502, 4,380)

−3.1

<0.002

6,000 cell/μL

0

94.5

5.5

1,770 (548, 4,778)

−5.1

<0.001

6,500 cell/μL

0

93

7

1,918 (593, 5,176)

−6.9

<0.001

7,000 cell/μL

0

92.9

7.1

2,065 (639, 5,574)

−7.9

<0.001

7,500 cell/μL

0

91.4

8.6

2,213 (684, 5,972)

−8.6

<0.001

8,000 cell/μL

0

89.8

10.2

2,360 (730, 6,370)

−9.4

<0.001

8,500 cell/μL

0

87.5

12.5

2,508 (776, 6,768)

−9.7

<0.001

9,000 cell/μL

0

85.2

14.8

2,656 (821, 7,166)

−9.8

<0.001

9,500 cell/μL

0

82.4

17.6

2,803 (867, 7,564)

−9.8

<0.001

10,000 cell/μL

0

77.2

22.8

2,950 (913, 7,963)

−9.8

<0.001

10,500 cell/μL

0

74

26

3,098 (958, 8,361)

−9.8

<0.001

11,000 cell/μL

0

71.1

28.9

3,245 (1,004, 8,759)

−9.8

<0.001

  1. *Wilcoxon signed rank test, p-value <0.05 indicates statistically significant difference.
  2. p-value >0.05 indicates no statistically significant difference, thus the respective assumed TLCs to have most robust precision with measured TLC for the calculation of parasite index.
  3. Values in the assumed TLC row having robust precision with measured TLC are shown in bold face.