Table 3 Initial criteria for group allocation according to degree of prior exposure to Plasmodium falciparum
From: Lessons learnt from the first controlled human malaria infection study conducted in Nairobi, Kenya
Groups | Malaria exposure | Anti-Pf serology* | History of malaria infection | Time spent in endemic region |
|---|---|---|---|---|
1, 3, 5 | None | All negative | None | Lived whole life in Nairobi or similar area where P. falciparum is not endemic. |
2, 4, 6 | Maximal | High positive | +/- | Vast majority of life spent in western Kenya in area of high P. falciparum transmission. Immediately prior to CHMI, should not have spent more than 6 months out of endemic region. |