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Table 4 Final criteria for group allocation according to degree of prior exposure to Plasmodium falciparum

From: Lessons learnt from the first controlled human malaria infection study conducted in Nairobi, Kenya

Groups Malaria exposure Primary criterion: Secondary criterion:
Anti-Pf serology* Time spent in endemic region
1, 3, 5 Minimal All negative Lived majority of life in Nairobi or area where P. falciparum is not endemic.
2, 4, 6 Definite Positive anti-schizont +/- positive anti-MSP2 Considerable time spent in areas of P. falciparum transmission.
  1. *Anti-Pf serology = Anti-schizont and Anti-MSP2 antibodies.