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Table 4 Final criteria for group allocation according to degree of prior exposure to Plasmodium falciparum

From: Lessons learnt from the first controlled human malaria infection study conducted in Nairobi, Kenya

Groups

Malaria exposure

Primary criterion:

Secondary criterion:

Anti-Pf serology*

Time spent in endemic region

1, 3, 5

Minimal

All negative

Lived majority of life in Nairobi or area where P. falciparum is not endemic.

2, 4, 6

Definite

Positive anti-schizont +/- positive anti-MSP2

Considerable time spent in areas of P. falciparum transmission.

  1. *Anti-Pf serology = Anti-schizont and Anti-MSP2 antibodies.