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Table 5 Frequency of complications in malaria patients

From: Clinical profile of Plasmodium falciparum and Plasmodium vivax infections in low and unstable malaria transmission settings of Colombia

Criteria P. falciparum P. vivax p value a
n (%) n (%)
One complication 43 42  
Hepatic dysfunction (TB >3 mg/dL) 8 (15.1) 12 (26.1) ns
Hepatic dysfunction (ALT > 120 U/L) 12 (22.6) 2 (4.3) 0.001
Renal dysfunction (serum creatinine > 1.5 mg/dL or BUN > 40 mg/dL) 7 (13.2) 7 (15.2) ns
Prostration 6 (11.3) 5 (10.9) ns
Haemoglobinuria (urine dipstick) 1 (1.9) 9 (19.6) 0.005
Respiratory distress 1 (1.9) 3 (6.5) ns
Hyperparasitaemia (>50,000 asexual parasites/μL) 3 (5.7) 1 (2.2) ns
Abnormal spontaneous bleeding 3 (5.7) 0 (0.0) NA
Severe anaemia (Hb < 7 g/dL) 1 (1.9) 2 (4.3) ns
Cardiogenic shock/systolic dysfunction (SBP < 70 mm Hg) 1 (1.9) 0 (0.0) NA
Severe thrombocytopaenia (≤20,000 platelets/μL) 0 (0.0) 1 (2.2) NA
More than one complication 10 4  
Hyperparasitaemia plus    
 Severe thrombocytopaenia 2 (3.8) 0 (0.0) NA
  Hepatic dysfunction 1 (1.9) 1 (2.2) ns
 Renal dysfunction 1 (1.9) 0 (0.0) NA
  Respiratory distress 1 (1.9) 0 (0.0) NA
  Severe anaemia 1 (1.9) 0 (0.0) NA
  Haemoglobinuria 0 (0.0) 1 (2.2) NA
Hepatic dysfunction plus    
  Prostration 2 (3.8) 0 (0.0) NA
  Severe thrombocytopaenia 1 (2.2) 0 (0.0) NA
  Renal dysfunction 1 (1.9) 0 (0.0) NA
Renal dysfunction plus    
  Prostration 0 (0.0) 1 (2.2) NA
  Abnormal spontaneous bleeding 1 (1.9) 0 (0.0) NA
  1. ap value using the Fisher’s exact test. ALT, alanine aminotransferase; BUN, blood urea nitrogen; Hb, haemoglobin; NA, not applicable; ns, not significant; SBP, systolic blood pressure; TB, total bilirubin. Most frequent and significant data are highlighted in bold.