Study region and design. A) South America. B) Southeastern Brazilian Atlantic forest. SP: São Paulo state, MG: Minas Gerais state, RJ: Rio de Janeiro state, PR: Paraná state, SC: Santa Catarina state. C) Landscapes 1–5 (10 sq km) representing spatial scale in which dynamics of malaria transmission can occur, given the estimated home ranges of vectors and parasites. Source: SOS Mata Atlântica, Instituto Nacional de Pesquisas Espaciais (INPE), 2008.