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Table 2 Inter-day assay precision and accuracy for LUME and 97–63 in rat plasma

From: Simultaneous quantification of proposed anti-malarial combination comprising of lumefantrine and CDRI 97–78 in rat plasma using the HPLC–ESI-MS/MS method: application to drug interaction study

  LUME (ng/mL) 97-63 (ng/mL)
  3.9 10 100 400 3.9 10 100 400
Meana 3.8 9.7 98.1 399.9 4.0 10.2 103.7 402.3
SD 0.23 0.46 5.37 18.94 0.23 0.48 4.11 16.45
Precision (%)b 5.90 4.72 5.48 4.74 5.77 4.75 3.97 4.09
Accuracy (%)c 98.11 96.87 99.42 99.99 102.55 108.38 103.72 100.58
  1. a n = 18; three days with six replicates per day.
  2. b Expressed as % RSD = (SD/mean) × 100.
  3. c Calculated as (mean determined concentration/nominal concentration) × 100.