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Table 1 New insecticidal products for malaria vector control

From: Implementation of the global plan for insecticide resistance management in malaria vectors: progress, challenges and the way forward

Intervention Status
Indoor residual sprays Two new long-lasting formulations of existing IRS insecticides but with increased longevity beyond the benchmark of 2–4 months, to 6–12 months have already reached the market. Other formulations of repurposed agro-chemicals are under development, but are at best 12–24 months from becoming available for deployment. IVCC has established a portfolio of novel active ingredient candidates that should deliver new public health insecticides by 2022.
Long-lasting insecticidal nets New formulations are in preparation, with the first generation of these containing a pyrethroid plus a synergist or growth regulator. An important step will be to examine potential additional benefits against pyrethroid-resistant Anopheles. A second generation of non-pyrethroid multi-insecticide nets is in early stage development but it is likely to be several years before availability for wide-scale deployment.
Spatial repellents Currently there are insufficient data to assess whether spatial repellents could play a substantive role in malaria disease prevention. A multi-country field trial of the effectiveness of repellents is under way which should establish whether repellents work against most or just a small sub-set of mosquito vectors, but this study is unlikely to alone provide sufficient evidence to recommend wide-scale usage of repellents as part of national control programmes. Continued commitment from industry and research groups will be required to identify and validate any promising new candidates.
  1. Information provided by the IVCC.