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Table 3 Treatment outcome: studies conducted in non endemic countries with >10 patients and follow up data available

From: The hyper-reactive malarial splenomegaly: a systematic review of the literature

Study

Country

N patients

Treatment

Duration

Follow up

Outcome

Van den Ende et al. 2000 [42]

Belgium

39 Caucasians, 17 fully responding to Fakunle criteria

Single, short term treat for Pf malaria (various regimens)

1 day to 1 week according to drug

≥2 wks (average 6 wks)

All not re-exposed improved or fully recovered

Eseme et al. 2004 [43]

Italy

49 Caucasians (29 fully responding to Fakunle criteria) plus 8 Africans (different countries)

Single, short term treatment for falciparum malaria (various regimens)

1- 4 days according to drug

6-36 mths

All not re-exposed improved or fully recovered

Puente et al. 2001 [83]

Spain

14 Africans (13 from E. Guinea, 1 from Cameroon)

Quinine standard dose for 1 wk then CLQ

3- 9 mths (mean = 4.3 mths)

3 - 9 mths (mean = 4.3 mths)

All not re-exposed improved or fully recovered