Estimated parameters and covariate effects along with uncertainty relative to the reference value. The light grey shaded region represents clinically irrelevant effect (+/- 20%) region. Numbers outside the shared region represent the approximate probability of the effect to be clinically relevant. Numbers inside the region represent the probability distribution within the clinically irrelevant region on either side of the reference line. FARM1 = Bioavailability for NVP-arm; FARM2 = Bioavailability for EFV-arm; CLARM1 = clearance for NVP-arm; CLARM2 = clearance for EFV-arm.