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Table 3 Factors associated with treatment failure among asymptomatic parasitaemic women treated with sulphadoxine-pyrimethamine at day 0

From: In vivo efficacy of sulphadoxine-pyrimethamine for the treatment of asymptomatic parasitaemia in pregnant women in Machinga District, Malawi

 

Univariable

Multivariable

  

95% CI

  

95% CI

 
 

HR

Lower

Upper

p-value

HR

Lower

Upper

p-value

Treatment failure, uncorrected by PCR

        

ITN use last night (reference: no ITN use last night)

0.54

0.32

0.92

0.02

0.67

0.38

1.16

0.16

Age: comparing >20 years to ≤20 years

0.68

0.44

1.06

0.09

    

Schooling years (continuous)

1.01

0.94

1.09

0.72

    

Log parasite density (continuous)

0.96

0.79

1.17

0.70

    

Gravidity: comparing multigravid to primigravid

0.48

0.31

0.74

<0.001

0.53

0.34

0.83

0.006

Treatment failure, corrected by PCR

        

ITN use last night (reference: no ITN use last night)

0.54

0.27

1.09

0.09

0.73

0.35

1.52

0.40

Age: comparing >20 years to ≤20 years

0.62

0.35

1.10

0.10

    

Schooling years (continuous)

1.05

0.95

1.15

0.35

    

Log parasite density (continuous)

0.97

0.75

1.25

0.79

    

Gravidity: comparing multigravid to primigravid

0.41

0.23

0.73

0.002

0.45

0.25

0.82

0.009

  1. HR = hazard ratio, CI = confidence interval, ITN = insecticide-treated bed net, PCR = polymerase chain reaction.