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Table 3 Factors associated with treatment failure among asymptomatic parasitaemic women treated with sulphadoxine-pyrimethamine at day 0

From: In vivo efficacy of sulphadoxine-pyrimethamine for the treatment of asymptomatic parasitaemia in pregnant women in Machinga District, Malawi

  Univariable Multivariable
   95% CI    95% CI  
  HR Lower Upper p-value HR Lower Upper p-value
Treatment failure, uncorrected by PCR         
ITN use last night (reference: no ITN use last night) 0.54 0.32 0.92 0.02 0.67 0.38 1.16 0.16
Age: comparing >20 years to ≤20 years 0.68 0.44 1.06 0.09     
Schooling years (continuous) 1.01 0.94 1.09 0.72     
Log parasite density (continuous) 0.96 0.79 1.17 0.70     
Gravidity: comparing multigravid to primigravid 0.48 0.31 0.74 <0.001 0.53 0.34 0.83 0.006
Treatment failure, corrected by PCR         
ITN use last night (reference: no ITN use last night) 0.54 0.27 1.09 0.09 0.73 0.35 1.52 0.40
Age: comparing >20 years to ≤20 years 0.62 0.35 1.10 0.10     
Schooling years (continuous) 1.05 0.95 1.15 0.35     
Log parasite density (continuous) 0.97 0.75 1.25 0.79     
Gravidity: comparing multigravid to primigravid 0.41 0.23 0.73 0.002 0.45 0.25 0.82 0.009
  1. HR = hazard ratio, CI = confidence interval, ITN = insecticide-treated bed net, PCR = polymerase chain reaction.