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Table 1 Anti-malarial activity of different doses of Echinops kebericho roots against Plasmodium berghei in Swiss albino mice

From: In vivo antiplasmodial and toxicological effect of crude ethanol extract of Echinops kebericho traditionally used in treatment of malaria in Ethiopia

Treatment groups

% survival of animal on day 10

% parasitaemia

% chemosuppression

Negative control

72.30 ± 2.37

62.40 ± 2.94

00.00 ± 0.00

200 mg/kg EKM

77.20 ± 2.51

51.83 ± 4.93

16.93 ± 1.17

350 mg/kg EKM

81.50 ± 1.40

44.02 ± 0.72*

29.46 ± 1.93

500 mg/kg EKM

95.80 ± 1.86*

26.65 ± 1.01*

57.29 ± 1.76

25 mg/kg CQ

100.00 ± 0.00*

00.00 ± 0.00*

100.00 ± 0.00

  1. Results are expressed as means ± S E M, n = 5. *P < 0.001 versus negative control