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Fig. 10 | Malaria Journal

Fig. 10

From: Optimization of a multi-well colorimetric assay to determine haem species in Plasmodium falciparum in the presence of anti-malarials

Fig. 10

Haem fractionation profiles for pyrimethamine. Percentages of ‘free’ haem (a) and Hz (b) are shown at increasing concentrations of PYR. No statistical difference exists between the total haem Fe per cell of all PYR treated cells and untreated cells (c). The amount of ‘free’ haem Fe (d) and Hz Fe (e) are shown at increasing concentrations of PYR. PYR IC50 as determined in D10 = 44 ± 6.8 nM

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Malaria Journal

ISSN: 1475-2875

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