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Table 1 Study population characteristics of Papua New Guinean women

From: Malaria preventive therapy in pregnancy and its potential impact on immunity to malaria in an area of declining transmission

Characteristic

Single course of CQ and SP treatment (nā€‰=ā€‰304)

Three courses of SP and AZ treatment (nā€‰=ā€‰277)

P-value

Age, years

24.0 (21.0ā€“28.0)

24.0 (21.0ā€“28.0)

0.2

Weight at enrolment, kg

55.0 (50.0ā€“59.0)

53.0 (49.0ā€“59.0)

0.6

MUAC at enrolment, cm

23.0 (22.0ā€“25.0)

23.0 (22.0ā€“25.0)

0.5

Gravidity

Ā Ā 

0.4

Gravida 1, n (%)

108 (35.5)

92 (33.2)

Gravida 2, n (%)

91 (29.9)

88 (31.8)

Gravida 3, n (%)

105 (34.5)

97 (35.0)

Overall Bed net use

Ā Ā 

0.4

No, n (%)

2 (0.7)

0 (0.0)

Intermittent, n (%)

89 (29.3)

82 (29.6)

Regular, n (%)

213 (70.1)

195 (70.4)

Ethnicity

Ā Ā 

0.5

Madang/Morobe

194 (63.8)

193 (69.7)

Sepik

57 (18.8)

41 (14.8)

Highland

26 (8.6)

19 (6.9)

Others

27 (8.9)

24 (8.7)

Residence

Ā Ā 

0.9

Urban

51 (16.8)

44 (16.0)

Peri-urban

59 (19.5)

50 (18.1)

Rural

181 (59.7)

170 (61.8)

Migrant

12 (4.0)

11 (4.0)

Light microscopy (P. falciparum)

Ā Ā Ā 

Enrolment (peripheral blood)

20 (6.6)

15 (5.4)

0.5

Delivery (peripheral blood)

7 (2.3)

5 (1.8)

0.7

Delivery (placental blood)

7 (2.3)

4 (1.4)

0.2

qPCR (P. falciparum)

Ā Ā Ā 

Enrolment (peripheral blood)

31 (10.2)

24 (8.7)

0.8

Delivery (peripheral blood)

14 (4.6)

8 (2.9)

0.1

Delivery (placental blood)

7 (2.3)

1 (0.3)

0.1

Placental histology

Ā Ā 

0.1

Uninfected

171 (81.8)

170 (81.0)

Infecteda

38 (18.2)

40 (19.1)

  1. Data represented as median and interquartile range, unless otherwise indicated
  2. AZ azithromycin, CQ chloroquine, SP sulfadoxine-pyrimethamine, MUAC mid-upper arm circumference
  3. aPlacental malaria was defined as histological evidence of acute, chronic, or past infection