Fig. 3From: P-selectin is a host receptor for Plasmodium MSP7 ligandsFull length PfMSP7 forms multimers and directly interacts with P-selectin with high avidity. a Purified recombinant full-length PfMSP7 was resolved by size-exclusion chromatography and eluted as a polydisperse peak. This was typical of more than ten independent preparations, though some elution profiles showed additional peaks at higher elution volumes. b Analysis of the PfMSP7/P-selectin interaction by SPR. A dilution series of the major peak of resolved PfMSP7 was sequentially injected over P-selectin immobilized on a streptavidin-coated sensor chip. SPR responses upon 20Â s injections of the indicated concentrations of purified PfMSP7 analyte over P-selectin baitBack to article page