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Fig. 1 | Malaria Journal

Fig. 1

From: Characterization of the infectious reservoir of malaria with an agent-based model calibrated to age-stratified parasite densities and infectiousness

Fig. 1

Calibration of asexual parasite and gametocyte densities. a The distribution of asexual parasite and gametocyte densities by season and age group in reference data (open circles) and post-calibration simulation (filled circles) is shown for two study sites. Circle area is proportional to number of individuals and normalized for each season of each age group. b Example infection trajectories of asexual parasites (blue) and gametocytes (green) after calibration for an age-6 child (solid lines) and age-28 adult (dotted lines) with immune histories corresponding to high-transmission (top) and low-transmission (bottom) settings. Each individual was challenged with a single infectious bite on day 0, with no subsequent biting. No drugs were administered and host immunity eventually cleared all parasites

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Malaria Journal

ISSN: 1475-2875

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