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Table 1 Exflagellation-blocking activitya of dihydroartemisinin (DHA), methylene blue (MeBlue) and chloroquine (CQ) against Plasmodium falciparum field isolates and the 7G8 reference strain

From: Use of Plasmodium falciparum culture-adapted field isolates for in vitro exflagellation-blocking assay

  7G8 Q188 Q206 6831 6836
DHA 99 ± 1.3 90 ± 8.3 78 ± 7.2 84 ± 12.2 79 ± 11.6
MeBlue 100 100 99 ± 1.7 100 99 ± 2.1
CQ −1 ± 10.8 ND 5.7 ± 10.2 ND 7.3 ± 19.2
  1. aExpressed as a percentage of inhibition compared to the drug-free control (mean ± SEM, n = 3)
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Malaria Journal

ISSN: 1475-2875

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