Modified mosquito landing boxes dispensing transfluthrin provide effective protection against Anopheles arabiensis mosquitoes under simulated outdoor conditions in a semi-field system

Table 3 Effect of age on the estimated time for knock down of 50% of the mosquitoes (KD50) and toxicity of transfluthrin-impregnated strips when mosquitoes are exposed in a cylinder assay

Age of transfluthrin strip	Estimated KD50 (min) [IQR]	24-h mortality [95% CI]	24-h mortality OR [95% CI]	z value	p value
Control	–	6.13% [2.9–9.37]	–	–	–
24 h	2 [1–2]	91% [86.26–95.14]	265.8 [180.41–391.65]	28.23	<0.001
1 week	2 [1–3]	76.29% [68.17–84.41]	72.97 [52.48–101.46]	25.51	<0.001
2 weeks	4 [2–6]	54.04% [46.33–61.75]	24.44 [17.88–33.41]	20.03	<0.001
3 weeks	7 [5–10]	28.15 [22.57–33.72]	6.89 [3.64–7.37]	5.02	<0.001

KD50 in minutes was estimated from Kaplan–Meier survival curve. The 24-h mortality statistical parameters were estimated by fitting a mixed effect logistic regression model.
24-h mortality OR of strips of different age compared to the control strips gets lower the older the strips are. However, 3-week old strips still kill significantly more mosquitoes than control strips.
OR odds ratio, CI confidence intervals.

ISSN: 1475-2875