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Figure 1 | Malaria Journal

Figure 1

From: Tumour necrosis factor allele variants and their association with the occurrence and severity of malaria in African children: a longitudinal study

Figure 1

Associations of TNF genotype with time to first episode of malaria. Values indicate the number of children, by TNF genotype group, who had remained free of malaria at 0, 100, 200, 300, and 400 days of follow-up. For TNF −1031 (rs1799964) allele variant (top panel), pairwise group comparison with the wild type genotype as the reference group yielded p-values of 0.78 and 0.74 for heterozygotes rs1799964 TC and homozygotes (rs1799964 CC), respectively; for the TNF −308 allele variant (bottom panel), corresponding p-values for heterozygotes (TNF −308GA) and homozygotes (TNF −308AA) were 0.54 and 0.31, respectively (Peto tests). For homozygotes of the TNF −308A allele (TNF −308AA), the curve is not shown because only one episode occurred at 400 days of follow-up.

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Malaria Journal

ISSN: 1475-2875

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