Skip to main content

Table 1 Ex vivo susceptibility of Plasmodium falciparum isolates by drug tested

From: Ex vivo anti-malarial drug susceptibility of Plasmodium falciparum isolates from pregnant women in an area of highly seasonal transmission in Burkina Faso

 

Culture success rate % (n/N)

Geometric Mean IC50 (nM) [95% CI]

Range

Resistant isolates n (%)

MDAQ

80.6 (87/108)

1.5 [1.0–2.2]

0.1

158.5

7 (8.0)

MQ

80.6 (87/108)

1.1 [0.8–1.7]

0.02

103.7

8 (9.2)

DHA

79.6 (86/108)

1.2 [0.9–1.6]

0.1

10.2

NA*

CQ

78.7 (85/108)

40.1 [28.6–58]

1.2

1060.1

20 (23.5)

LUM

78.7 (85/108)

1.4 [1.0–2.1]

0.1

97.7

NA

QN

83.3 (90/108)

34.2 [24.1–48.5]

1.9

995.5

4 (4.4)

PiP

76.8 (83/108)

5.0 [4.1–6.3]

0.5

47.9

NA

  1. Resistance threshold defined for CQ at 100 nM, QN at 800 nM, MQ at 30 nM and MDAQ at 60 nM.
  2. * NA not applicable as the threshold is not defined yet.