Figure 2

Hybrid Metapopulation DE-IBM Model flow. a Compartment transmission model for each patch i (1–6) with sub-patch j (1–3) at time step t with compartments S susceptible, I infectious and treated (tr), C infectious, symptomatic and untreated (u), A infectious, asymptomatic and untreated, M Infectious, sub-patent and untreated and P susceptible with prior asymptomatic infection. b) Metapopulation structure highlighting human movement between each local patch \(i \ \epsilon \ \lbrace 1,2,3,4,5 \rbrace\) and foreign patch 6. Other parameters are described in Table 1 and Additional file 1.