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Table 1 Quantification of small VSA localizations within infected erythrocytes

From: A comparative study of the localization and membrane topology of members of the RIFIN, STEVOR and PfMC-2TM protein families in Plasmodium falciparum-infected erythrocytes

VSA family Antiserum Parasite Maurer’s clefts Erythrocyte membrane
Trophozoite (%) Schizont (%) Trophozoite (%) Schizont (%) Trophozoite (%) Schizont (%)
RIFIN α-RIF40.2 86.4 100.0 14.6 33.1 37.9 53.5
α-RIF44 100.0 99.1 10.0 36.1 87.5 83.3
STEVOR α-PFL2610w 75.7 100.0 1.9 1.9 100.0 95.2
α-MAL13P1.7 67.9 100.0 0.9 0.9 100.0 84.9
α-PFC0025c 18.8 64.3 87.5 78.6 83.0 87.5
α-PFA0750w 2.4 8.3 41.7 94.4 100.0 100.0
PfMC-2TM α-PfMC-2TM-SC 0.0 63.3 5.9 18.0 100.0 36.8
α-PfMC-2TM-CT 79.0 100.0 9.7 5.7 55.3 31.1
  1. RIFIN, STEVOR and PfMC-2TM protein localization was quantified in trophozoite and schizont stage parasites according to their detection within the parasite, at the Maurer’s clefts and at the erythrocyte membrane. At least 100 positively stained cells were counted for each staining, however, the summary percentage of all location sites is greater than 100 because some proteins localized to multiple sites within one cell.