Table 2 Summary of formulations tested with the brand name, manufacturer, dose, dosage form, ACT Watch Antimalarial database status and WHO prequalification list
Brand name/manufacturer | Generic name and dose | ACT Watch Antimalarial Database Antimalarial category | Regulatory status in Gabon |
|---|---|---|---|
Alaxin-SP®, Bliss GVS Pharma LTD, India | Dihydroartemisinin + SP tablet 60/500/25 mg | Non-quality assured ACT | Unknown |
Arco®, Kunming Pharmaceutical Corp, China | Artemisinin-naphthoquine tablet 125/50 mg | Non-quality assured ACT | Unknown |
Arsiquinoforme®, Sanofi Aventis, Cote d’Ivoire | Quinine tablet 250 mg | Non-artemisinin therapy | Unknown |
Artecom®, Tonghe Pharmaceutical Co. Ltd, China | Dihydroartemisinin-piperaquine-trimethoprim tablet 32/320/90 mg and 16/160/45 mg | Non-quality assured ACT | Unknown |
Artedar®, Plethico Pharma Ltd, India | Artesunate-SP, tablet 100/500/25 mg | Non-quality assured ACT | Unknown |
Artediam®, Adams Pharmaceutical (Anhui) Co., Ltd. | Artesunate-amodiaquine tablet 100/300 mg | Not listed, category unknown. | Approval at national level |
Artefan®, Ajanta Pharma Ltd, India | Artemether-lumefantrine tablet 20/120 mg Artemether-lumefantrine tablet 80/480 mg | QAACT (Quality-assured ACT) Non-quality assured ACT | A (MA092, 2012-Dec-19)—WHO prequalification Approval at national level |
Artequick®, Artepharm Co.Ltd, China | Artemisinin-piperaquine tablet 62.5/375 mg | Non-quality assured ACT | Unknown |
Artequin®, Mepha Ltd, Switzerland | Artesunate-mefloquine tablet 200/250 mg Artesunate-mefloquine tablet 100/125 mg | QAACT (Quality-assured ACT) Non-quality assured ACT | B |
Artim®, Twight Litaka Pharma Limited Ltd, India | Artemether-lumefantrine tablet 40/240 mg | Not listed, category unknown | Unknown |
Artiz (Forte)®, Alice Pharma Pvt Ltd, India | Artemether-lumefantrine tablet 40/240 mg Artemether-lumefantrine tablet 20/200 mg | Dosage not listed, category unknown Dosage not listed, category unknown | Unknown |
ASAQ Denk®, Denk Pharma, Germany | Artesunate-amodiaquine tablet 100/270 mg | Non-quality assured ACT | Unknown |
Asunate Denk®, Denk Pharma, Germany | Artesunate-SP tablet 200/500/25 mg | Non-quality assured ACT | Unknown |
Bimalaril®, Bengba Pharmaceutical factory, China | Artemether-lumefantrine tablet 80/480 mg | Not listed, manufacturer unknown | Approval at national level |
Chinther®, Alkema Laboratories LTD, India | Artemether-lumefantrine tablet 40/240 mg | Not listed, brand and manufacturer unknown | Unknown |
Co-Arinate®, Famar Italia Spa, Italy | Artesunate-SP tablet 200/500/25 mg Artesunate-SP tablet 100/250/12,5 mg | Not listed, manufacturer unknown Not listed, manufacturer unknown | Unknown |
Coarsucam®, Sanofi Aventis, Morocco | Artesunate-amodiaquine tablet 50/135 mg Artesunate-amodiaquine tablet 100/270 mg Artesunate-amodiaquine tablet 25/67.5 mg | QAACT (Quality-assured ACT) QAACT (Quality-assured ACT) QAACT (Quality-assured ACT) | MA057 (2008-Oct-14)/MA058 2008-Oct-14/MA056 (2008-Oct-14) WHO prequalification |
Coartem®, Novartis Pharma Ag, China, Switzerland, USA | Artemether-lumefantrine tablet 20/120 mg | QAACT (Quality-assured ACT) | A-B (MA026 (a), 2004-Apr-26) WHO prequalification/FDA approval |
Co-artemax®, GA Pharma, Greece | Dihydroartemisinin-piperaquine tablet 40/320 mg | Not listed, brand & manufacturer unknown | Unknown |
Cofantrine®, Bliss Gvs Pharma Ltd, India Cofantrine®, EGR Pharma, Luxembourg | Artemether-lumefantrine tablet 20/120 mg and 80/470 mg Artemether-lumefantrine tablet 20/120 mg | Non-quality assured ACT Not listed, unknown manufacturer | Approval at national level |
Colart®, Glaxosmithkline Group Of Companies, India | Artemether-lumefantrine tablet 20/120 mg | Non-quality assured ACT | Unknown |
Combimal®, Ajanta Pharma Ltd, India/Mauritius | SP tablet 500/25 mg | Non-artemisinin therapy | Unknown |
Darte-Q®, Gosun Pharma Corp, China | Dihydroartemisinin-piperaquine tablet 40/320 mg | Non-quality assured ACT | Unknown |
Duo-Cotecxin®, Beijing Holley-Cotec Pharmaceutical Ltd, China | Dihydroartemisinin-piperaquine tablet 40/320 mg | Non-quality assured ACT | Unknown |
Falquin®, Plethico pharmaceutical Ltd, India | Quinine tablet 300 mg. | Not listed, manufacturer unknown | Unknown |
Fansidar®, F.Hoffmann La Roche Ltd, Switzerland | SP tablet 500/25 mg | Non-artemisinin therapy | Unknown |
Lariam®, F.Hoffmann La Roche Ltd, Switzerland | Mefloquine tablet 250 mg | Non-artemisinin therapy, country of manufacture not listed | Unknown |
Laritem®, IPCA Laboratories Ltd, India | Artemether-lumefantrine 20/120 mg Artemether-lumefantrine 80/480 mg | Non-quality assured ACT Dosage not listed | A (MA062, 2009-Dec-15) WHO prequalification |
Lufanter®, Bliss Gvs Pharma Ltd, India | Artemether-lumefantrine 20/120 mg and 80/480 mg | Non-quality assured ACT | Approval at national level |
Lumart®, Cipla Ltd, India | Artemether-lumefantrine tablet 20/120 mg Artemether-lumefantrine tablet 40/240 mg | QAACT (Quality-assured ACT) Dosage not listed | A (MA064, 2009-May-22) WHO prequalification |
Malacur®, Elder pharmaceuticals LTD, India | Dihydroartemisinin-piperaquine tablet 40/320 mg | Non-quality assured ACT Brand known, manufacturer not listed | Approval at national level |
Malanil®, Glaxosmithkline Group Of Companies, Canada | Atovaquone-proguanil tablet 250/100 mg | Non-artemisinin therapy | Unknown |
Maloxine®, Gracure Pharmaceuticals Ltd, India | SP tablet 500/25 mg | Non-artemisinin therapy Brand known, manufacturer not listed | Unknown |
Mephaquin®, Mepha Ltd, Switzerland | Mefloquine tablet 250 mg | Non-artemisinin therapy | Unknown |
P-Alaxin®, Bliss Gvs Pharma Ltd, India | Dihydroartemisinin-piperaquine tablet 40/320 mg | Non-quality assured ACT | Approval at national level |
Paludrine®, Astra Zeneca UK Limited, United Kingdom | Proguanil tablet 100 mg | Prophylaxis | B |
Pharmasucam®, Madras Pharmaceuticals, India | Artesunate-amodiaquine 100/270 mg | Not listed, brand name and manufacturer unknown | Unknown |
Quinimax®, Sanofi Aventis, Spain | Quinine 500 mg and 125 mg | Non-artemisinin therapy | Unknown |
R-Lume®, Impact Healthcare Pvt Ltd, India | Artemether-lumefantrine tablet 80/480 mg | Not listed, brand name and manufacturer unknown | Unknown |
Savarine®, AstraZeneca Ltd, France | Proguanil-chloroquine tablet 200/100 mg | Not listed | Unknown |
Sharlum®, Sharon Big-medicine Ltd, India | Artemether-lumefantrine tablet 80/480 mg and 40/240 mg | Not listed, brand name and manufacturer unknown | Unknown |
Surquina®, Laboratoire Innotech International, France | Quinine tablet 250 mg | Non-artemisinin therapy | Unknown |