Figure 4From: Isolation, production and characterization of fully human monoclonal antibodies directed to Plasmodium falciparum MSP10Alignment of Vh and Vl sequences of 5E8 and 5F6 with their respective germline sequence. The amino acid sequences of the obtained human antibody V region sequences rescued from LCLs 5E8 (a, b) and 5F6 (c, d) were aligned to their respective germline sequence, as obtained by the IMGT/V-Quest Tool [24]. Joining region elements containing N-nucleotides between the V-, D and J-segments for the Vh (a, c) are marked by the undefined amino acid X. CDR1-3 (boxes) are labelled according to the Kabat definition.Back to article page