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Figure 4 | Malaria Journal

Figure 4

From: Isolation, production and characterization of fully human monoclonal antibodies directed to Plasmodium falciparum MSP10

Figure 4

Alignment of Vh and Vl sequences of 5E8 and 5F6 with their respective germline sequence. The amino acid sequences of the obtained human antibody V region sequences rescued from LCLs 5E8 (a, b) and 5F6 (c, d) were aligned to their respective germline sequence, as obtained by the IMGT/V-Quest Tool [24]. Joining region elements containing N-nucleotides between the V-, D and J-segments for the Vh (a, c) are marked by the undefined amino acid X. CDR1-3 (boxes) are labelled according to the Kabat definition.

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