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Table 4 IgG levels to RESA antigens in responder children according to host and parasite characteristics

From: Immunoglobulin response to Plasmodium falciparum RESA proteins in uncomplicated and severe malaria

Group

rRESA-1B

rRESA-3B

P1

P2

P3

P4

P5

P6

SM

0.7 [0.3–1.7] (28)a

0.1 [0.1–0.7] (19)

0.7 [0.5–1.0] (5)

0.9 [0.6–1.42] (27)

0.8 [0.7–1.4] (5)

1.2 [1.0–1.5] (2)

0.4 [0.2–0.5] (11)

0.6 [0.5–1.0] (5)

UM

1.1 [0.4–1.9] (27)

0.2 [0.1–0.5] (23)

0.5 [0.4–0.6] (10)

0.8 [0.6–1.1] (11)

0.6 [0.5–0.6] (5)

0.6 [0.5–0.7] (9)

0.2 [0.2–0.3] (7)

0.9 [0.5–1.3] (7)

P b

0.28

0.67

0.18

0.81

0.08

0.10

0.22

0.46

HbAA

0.7 [0.3–2.0] (43)

0.2 [0.1–0.5] (31)

0.5 [0.4–0.8] (11)

1.0 [0.7–1.4] (30)

0.7 [0.5–0.7] (8)

0.6 [0.5–0.7] (8)

0.2 [0.2–0.4] (13)

0.6 [0.4–1.1] (11)

HbAS or HbSS

0.7 [0.6–1.1] (9)

0.2 [0.2–0.6] (7)

0.5 [0.5–0.6] (2)

0.5 [0.5–1.0] (3)

1.8 [1.8–1.8] (1)

1.8 [1.8–1.8] (1)

0.3 [0.3–0.4] (4)

(0)

HbAC or HbCC

1.4 [0.8–1.8] (3)

0.5 [0.1–0.9] (4)

0.4 [0.4–0.5] (2)

0.6 [0.5–0.6] (5)

0.6 [0.6–0.6] (1)

0.7 [0.6–0.7] (2)

0.3 [0.3–0.3] (1)

0.9 [0.9–0.9] (1)

P

0.61

0.49

0.24

0.02

0.43

0.22

0.66

0.88

resa2 T1526G allele

0.9 [0.4–2.3] (8)

0.3 [0.1–0.4] (8)

0.4 [0.4–0.4] (3)

0.9 [0.7–1.3] (7)

0.6 [0.6–1.0] (3)

0.5 [0.5–0.5] (1)

0.3 [0.3–0.4] (2)

0.4 [0.4–0.4] (2)

no resa2 T1526G allele

0.7 [0.3–1.7] (47)

0.2 [0.1–0.8] (34)

0.6 [0.5–0.8] (12)

0.8 [0.6–1.4] (31)

0.7 [0.6–0.8] (7)

0.7 [0.5–0.7] (10)

0.3 [0.2–0.4] (16)

1.0 [0.6–1.1] (10)

P

0.45

0.90

0.04

0.95

0.91

0.53

0.57

0.08

  1. aMedian values [25th–75th percentiles] expressed in OD; (number of responders).
  2. b P value for the Mann–Whitney U test (two groups) or Kruskal–Wallis test (three groups); significant P value < 0.01.