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Table 4 IgG levels to RESA antigens in responder children according to host and parasite characteristics

From: Immunoglobulin response to Plasmodium falciparum RESA proteins in uncomplicated and severe malaria

Group rRESA-1B rRESA-3B P1 P2 P3 P4 P5 P6
SM 0.7 [0.3–1.7] (28)a 0.1 [0.1–0.7] (19) 0.7 [0.5–1.0] (5) 0.9 [0.6–1.42] (27) 0.8 [0.7–1.4] (5) 1.2 [1.0–1.5] (2) 0.4 [0.2–0.5] (11) 0.6 [0.5–1.0] (5)
UM 1.1 [0.4–1.9] (27) 0.2 [0.1–0.5] (23) 0.5 [0.4–0.6] (10) 0.8 [0.6–1.1] (11) 0.6 [0.5–0.6] (5) 0.6 [0.5–0.7] (9) 0.2 [0.2–0.3] (7) 0.9 [0.5–1.3] (7)
P b 0.28 0.67 0.18 0.81 0.08 0.10 0.22 0.46
HbAA 0.7 [0.3–2.0] (43) 0.2 [0.1–0.5] (31) 0.5 [0.4–0.8] (11) 1.0 [0.7–1.4] (30) 0.7 [0.5–0.7] (8) 0.6 [0.5–0.7] (8) 0.2 [0.2–0.4] (13) 0.6 [0.4–1.1] (11)
HbAS or HbSS 0.7 [0.6–1.1] (9) 0.2 [0.2–0.6] (7) 0.5 [0.5–0.6] (2) 0.5 [0.5–1.0] (3) 1.8 [1.8–1.8] (1) 1.8 [1.8–1.8] (1) 0.3 [0.3–0.4] (4) (0)
HbAC or HbCC 1.4 [0.8–1.8] (3) 0.5 [0.1–0.9] (4) 0.4 [0.4–0.5] (2) 0.6 [0.5–0.6] (5) 0.6 [0.6–0.6] (1) 0.7 [0.6–0.7] (2) 0.3 [0.3–0.3] (1) 0.9 [0.9–0.9] (1)
P 0.61 0.49 0.24 0.02 0.43 0.22 0.66 0.88
resa2 T1526G allele 0.9 [0.4–2.3] (8) 0.3 [0.1–0.4] (8) 0.4 [0.4–0.4] (3) 0.9 [0.7–1.3] (7) 0.6 [0.6–1.0] (3) 0.5 [0.5–0.5] (1) 0.3 [0.3–0.4] (2) 0.4 [0.4–0.4] (2)
no resa2 T1526G allele 0.7 [0.3–1.7] (47) 0.2 [0.1–0.8] (34) 0.6 [0.5–0.8] (12) 0.8 [0.6–1.4] (31) 0.7 [0.6–0.8] (7) 0.7 [0.5–0.7] (10) 0.3 [0.2–0.4] (16) 1.0 [0.6–1.1] (10)
P 0.45 0.90 0.04 0.95 0.91 0.53 0.57 0.08
  1. aMedian values [25th–75th percentiles] expressed in OD; (number of responders).
  2. b P value for the Mann–Whitney U test (two groups) or Kruskal–Wallis test (three groups); significant P value < 0.01.