Figure 1

IgG and IgM responses to gSG6-P1 salivary peptide, intensity of Plasmodium falciparum transmission and Anopheles exposure level in the first year of life. Individual IgG (1a) and IgM (1b) responses to the Anopheles gSG6-P1 peptide biomarker are represented for infants in months 3 (white), 6 (light-grey), 9 (dark-grey) and 12 (black box) after their birth. Boxes locate the middle 50% of the data; horizontal lines in the boxes indicate median values; lengths of boxes correspond to the inter-quartile ranges. Horizontal black dotted lines represent the cut-off of IgG (0.204) and IgM (0.288) responder. The intensity of P. falciparum infection (1c) and the entomological risk of malaria (1d) are also represented for the same four age-sampling periods. Vertical lines indicate confidence intervals of the mean values. Statistical significant differences between all age groups (multivariate linear mixed model analysis) are indicated.