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Table 1 Clinical-demographic profile of study participants (N = 125) with P. vivax monoinfection from southwestern India treated with chloroquine (25 mg/kg over 3 days) followed by primaquine (0.25 mg/kg daily for 14 days)

From: Therapeutic assessment of chloroquine–primaquine combined regimen in adult cohort of Plasmodium vivax malaria from a tertiary care hospital in southwestern India

Settings Outpatient (N = 41) Inpatient (N = 84) p value$
Variables Mean ± SD/median (IQR) Range Mean ± SD/median (IQR) Range
Age in years 33.6 ± 13.2 18–76 35.3 ± 13.3 18–73 0.49
Duration of fever in days 3 (2, 4) 1–30 4 (3, 6) 1–60 0.14
Axillary temperature at presentation (oC) 99.2 ± 1.0 98.6–102 100.3 ± 1.7 98.6–104 <0.001
Defervescence time in hours 8 (0, 17) 0–48 12 (4.5, 33.5) 0–148 0.001
Parasite index on day ‘0’ (parasites/µL) 1,164 (803–1,686)a 41–11,640 1,255 (932–1,690)a 64–21,700 0.17
  1. aGeometric mean with 95% confidence interval of geometric mean.
  2. $p value obtained by either independent t test or Mann–Whitney U test or Chi square test as applicable, p values <0.05 are shown in italic face.
Settings Outpatient (N = 41) Inpatient (N = 84) p value$
Variables Frequency (%) Frequency (%)
Gender (males) 39 (95.1) 71 (84.5) 0.14
Empiric antibiotics 0 1 (1.2) 1.00
Treatment failure 0 1 (1.2) 1.00
nPCR proven mixed malaria 3 (7.3) 5 (6) 0.72
  1. aGeometric mean with 95% confidence interval of geometric mean.
  2. $p value obtained by either independent t test or Mann–Whitney U test or Chi square test as applicable, p values <0.05 are shown in italic face.