Table 2 Results of logistic regression analysis investigating the effect of age, gender and HbS genotype on malaria status as determined by microscopya using combined data.
From: Genetic determinants of anti-malarial acquired immunity in a large multi-centre study
Factor | Adjusted OR (95 % CI) | p-value | Malaria status by microscopy | |||
|---|---|---|---|---|---|---|
Individuals positive (total = 1,966) | Individuals negative (total = 7,261) | |||||
N | (%) | N | (%) | |||
Age (years) | ||||||
<1 | 1 | 37 | (10.9) | 303 | (89.1) | |
1–2 | 1.33 (0.87–2.05) | 0.191 | 47 | (17.2) | 225 | (82.7) |
2–5 | 2.65 (1.88–3.72) | <0.001 | 311 | (26.7) | 854 | (73.3) |
5–15 | 3.49 (2.53–4.86) | <0.001 | 1,141 | (25.6) | 3,314 | (74.4) |
15–30 | 1.21 (0.87–1.70) | 0.263 | 281 | (17.1) | 1,365 | (82.9) |
>30 | 0.63 (0.44–0.90) | 0.010 | 147 | (11.1) | 1,177 | (88.9) |
Gender | ||||||
Female | 1 | 1,044 | (20.1) | 4,142 | (79.9) | |
Male | 1.09 (0.98–1.21) | 0.109 | 922 | (22.8) | 3,119 | (77.2) |
HbS | ||||||
11 | 1 | 1,824 | (21.4) | 6,718 | (78.6) | |
12 | 0.75 (0.61–0.92) | 0.005 | 136 | (21.1) | 508 | (78.9) |
22 | ND | ND | 0 | (0) | 8 | (100) |