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Table 5 Comparison of sensitivity and specificity of HtLAMP-Pg and HtLAMP-Pf for the detection of P. falciparum and non-falciparum species with other LAMP studies in symptomatic patients

From: A simple, high-throughput, colourimetric, field applicable loop-mediated isothermal amplification (HtLAMP) assay for malaria elimination

LAMP study Sample source Species LAMP primer Sensitivity (%) Specificity (%)
HtLAMP Symptomatic patients P. falciparum Pg 98 83
Pf 97 96
Polley et al. [23] Symptomatic patients P. falciparum Pg 93.9 100
Pf 93.3 100
Polley et al. [27] Symptomatic returned travellers P. falciparum Pg 97 99.2
Pf 98.4 98.1
Hopkins et al. [30] Passive case detection P. falciparum Pf 89–93.9 76.3–85
HtLAMP Symptomatic patients Non-falciparum Pg 100 83
Vallejo et al. [32] Symptomatic patients Non-falciparum Pg 91.4 91.8