Fig. 5
Comparison of the DC maturation state between LPS and synthetic peptides, S100A8, CSP, AMA-1, and MSP-1. DC maturation as determined by the expression levels of CD86, HLA-DR, and PDL-1 by several synthetic peptides. The relative increase in surface expression is expressed as the mean fluorescence intensity (MFI) of matured DCs over the MFI of iDCs. A representative result of three repeated experiments is shown for FACS analysis. Significant differences were determined using one-way ANOVA followed by Bonferroni’s multiple comparison tests (*P < 0.05, **P < 0.01, ***P < 0.001)