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Table 1 Utility of RDTs as a source of DNA for genotyping loci involved in diversity and drug resistance

From: RDTs as a source of DNA to study Plasmodium falciparum drug resistance in isolates from Senegal and the Comoros Islands

RDT Brand Number RDT HRMa HRMa PCRb PCRb Fragment used RDT
Positive Negative Positive Negative
SD Bioline malaria Rapid test pf 80 77 3 77 3 1/3 NC
SD Bioline malaria Ag Pf/Pan 13 13 0 13 0 1/3 NC
Malaria pLDH/HRP2 combo 111 111 0 110 1 1/3 NC
Total 204 201c 3 200 4
  1. aThe HRM method was used for genotyping dhfr and dhps genes
  2. bPCR was used to genotype msp1 and msp2
  3. cFor codons 51/59, only 62 samples from Thiès and 96 samples from Grande-Comore gave a comprehensive genotyping