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Table 1 Utility of RDTs as a source of DNA for genotyping loci involved in diversity and drug resistance

From: RDTs as a source of DNA to study Plasmodium falciparum drug resistance in isolates from Senegal and the Comoros Islands

RDT Brand

Number RDT

HRMa

HRMa

PCRb

PCRb

Fragment used RDT

Positive

Negative

Positive

Negative

SD Bioline malaria Rapid test pf

80

77

3

77

3

1/3 NC

SD Bioline malaria Ag Pf/Pan

13

13

0

13

0

1/3 NC

Malaria pLDH/HRP2 combo

111

111

0

110

1

1/3 NC

Total

204

201c

3

200

4

–

  1. aThe HRM method was used for genotyping dhfr and dhps genes
  2. bPCR was used to genotype msp1 and msp2
  3. cFor codons 51/59, only 62 samples from Thiès and 96 samples from Grande-Comore gave a comprehensive genotyping