Skip to main content

Table 3 Prevalence of point mutations found in dhfr/dhps genes from included studies

From: Falciparum malaria molecular drug resistance in the Democratic Republic of Congo: a systematic review

  Authors Year of collecting Dhps mutations Dhfr mutations Quint. mutant (dhfr and dhps) Wild
A437G K540E Double mutants N51I C59R S108N Triple mutants dhps dhfr both
1. Alker et al. 2002 72 % 67 % >95 % 66 % >95 % 43 % 1 %
2. Cohuet et al. 2003–2004 <20 % >50 % 0.9–12.8 % 29.4–75.6 % 1–3.9 %
3. Swarthout et al. 2004 0.6 % 45.2 % 3.2 % 46.2 % 27.1 % 30 % 7.6 % 3 %
4 Taylor et al. 2007 14.6 % 35.1 %
5. Mobula et al. 2008 93.1 % 9.5 % 97.9 % 80.7 % 99.1 %