Table 2 Inhibitory effects assessed with the HLC assay
μM | 15.6 | 31.25 | 62.5 | 125 | 250 | 500 | 1000 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P2.5 | P10 | P2.5 | P10 | P2.5 | P10 | P2.5 | P10 | P2.5 | P10 | P2.5 | P10 | P2.5 | P10 | |
Blood | ||||||||||||||
Chloroquine | + | + | + | + | – | – | – | – | – | – | – | – | – | – |
Amodiaquine | + | + | + | + | – | – | – | – | – | – | – | – | – | – |
Quinine | + | + | + | + | – | + | – | – | – | – | – | – | – | – |
Piperaquine | + | + | + | + | – | – | – | – | – | – | – | – | – | – |
Halofantrine | + | + | + | + | + | + | + | – | – | – | – | – | – | – |
Mefloquine | + | + | + | + | + | + | + | + | – | + | – | – | – | – |
Artemisinin | + | + | + | + | + | + | + | + | + | + | – | – | – | – |
Artesunate | + | + | + | + | + | + | + | – | – | – | – | – | – | – |
Doxycycline | + | + | + | + | + | + | + | + | + | + | – | + | – | – |
Rolitetracycline | + | + | + | + | + | + | + | + | + | – | – | – | – | – |
Tetracycline | + | + | + | + | + | + | + | + | + | – | + | – | + | – |
Pyrimethamine | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
Gentamicin | + | + | + | + | + | + | + | – | + | – | + | – | + | – |
Haemin | ||||||||||||||
Chloroquine | + | + | + | + | – | – | – | – | – | – | – | – | – | – |
Amodiaquine | + | + | + | + | – | – | – | – | – | – | – | – | – | – |
Quinine | + | + | + | + | + | + | – | – | – | – | – | – | – | – |
Piperaquine | + | + | + | + | + | – | – | – | – | – | – | – | – | – |
Halofantrine | + | + | + | + | + | + | + | + | – | – | – | – | – | – |
Mefloquine | + | + | + | + | + | + | + | + | – | + | – | – | – | – |
Artemisinin | + | + | + | + | + | + | + | – | – | – | – | – | – | – |
Artesunate | + | + | + | + | + | – | – | – | – | – | – | – | – | – |
Doxycycline | + | + | + | + | + | + | + | + | + | + | – | + | – | – |
Rolitetracycline | + | + | + | + | + | + | + | + | + | – | + | – | + | – |
Tetracycline | + | + | + | + | + | + | + | + | + | + | – | – | – | – |
Pyrimethamine | + | + | + | + | + | + | + | + | + | + | + | + | + | + |
Gentamicin | + | + | + | + | + | – | + | – | + | – | + | – | + | – |