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Table 1 Basic clinical and parasitological characteristics of patients in the cohort with malarial episodes

From: Artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in Congolese children under 10 years old living in a suburban area: a randomized study

 

ASAQ

AL

P

Number of patients

129

133

 

Age (months), mean (±SD)

64.9 ± 33.0

65.0 ± 30.6

1

Sex: female/male

42/70

57/76

0.09

Weight (kg), mean (±SD)

19.8 ± 6.3

19.6 ± 5.6

0.8

Axillary temperature (°C), mean (±SD)

38.0 ± 1.0

37.6 ± 1.3

0.5

GMPD, asexual parasites/µL

29,100

30,700

0.5

 Range

950–388,000

800–725,000

 

 PD <1000, N (%)

4 (3.1)

3 (2.3)

1

 PD 1000–200,000, N (%)

110 (85.3)

112 (84.2)

0.7

 PD ≥200,000, N (%)

15 (11.6)

18 (13.5)

0.5

Mean haemoglobin, g/dL (±SD)

10.6 (1.1)

10.5 (1.3)

0.5

 Anaemia (Hb < 11 g/dL), N (%)

75 (58.1 %)

78 (58.6)

0.9

AA genotype, N (%)

112 (86.8)

109 (82.0)

0.4

 GMPD, asexual parasites/µL

29,500

30,300

0.8

 Range

950–376,000

800–725,000

 

AS genotype, N (%)

17 (13.2)

24 (18.0)

0.3

 GMPD, asexual parasites/µL

19,000

39,300

0.0001

 Range

950–388,000

3360–487,000

 
  1. Anaemia was defined as haemoglobin (Hb) <11 g/dL
  2. GMPD geometric mean parasite density, PD parasite density