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Table 3 Efficacy of ASAQ and AL as first-line and second-line treatments

From: Artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in Congolese children under 10 years old living in a suburban area: a randomized study

 

First treated malaria episode

≥Second treated malaria episode

 

ASAQ

 ACPR, N (%)

59 (98.3)

37 (94.9)

RR = 1.04 (0.96–1.12)

 Recrudescence, N (%)

1 (1.7)

2 (5.1)

P = 0.3

 New infection

3

5

 

 Lost-to-follow-up

15

7

 

AL

 ACPR, N (%)

69 (94.5)

37 (100.0)

RR = 0.95 (0.89–1.00)

 Recrudescence, N (%)

4 (5.5)

0

P = 0.19

 New infection

4

4

 

 Lost-to-follow-up

10

5

 
 

RR = 1.04 (0.98–1.11), P = 0.2

RR = 0.95 (0.88–1.02), P = 0.26

 
  1. ASAQ artesunate-amodiaquine, AL artemether-lumefantrine, ACPR adequate clinical and parasitological response