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Table 1 Characteristics of the single-arm studies included in the review

From: A systematic review of the efficacy of a single dose artemisinin–naphthoquine in treating uncomplicated malaria

Study author, year of publication [reference]

Country

Main parasite species

Drug schedule

Brand (manufacture)

Dosing

28 day cure rate, n (%)

PCT

FCT

Wang et al., 2003 [6]

China

P. falciparum

Single dosea

Co-NQ (KPC)

8 Tabs (1000 mg ART + 400 mg NQ)

97/100 (97)

30 ± 8

17.5 ± 12.3

Nour et al., 2013 [10]

Sudan

P. falciparum

Single dose

ARCO (KPC)

8 Tabs (1000 mg ART + 400 mg NQ)

120/122 (98.4)

34.8 ± 12.6

12 ± 4.8

Tun et al., 2009 [11]

Myanmar

P. falciparum

Single dose

ASNQ (KPC)

 

52/53 (98.1)

34.6 ± 14.3

18.2 ± 8.6

  1. ART artemisin; ASNQ artemisinine-naphthoquine; Co-NQ artemisinine-naphthoquine; FCT fever clearance in hour; KPC Kunming Pharmaceutical Corporation, China; NA not available; PCT parasite clearance in hour; tabs tablets
  2. aCompared with artemisinine alone or naphthoquine alone