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Table 2 Standard curves equation of six probe substrates in inactive RLM

From: Impact of chrysosplenetin on the pharmacokinetics and anti-malarial efficacy of artemisinin against Plasmodium berghei as well as in vitro CYP450 enzymatic activities in rat liver microsome

Probe substrates Calibration curves R value Linear range (μM)
PN Y = 9.486X + 0.3485 0.9999 0.5–111
CA Y = 6.730X + 0.7809 0.9999 0.7–137
OPZ Y = 4.148X + 2.1741 0.9999 0.5–141
DM Y = 24.868X + 5.1424 0.9999 0.5–54
CLZ Y = 20.918X + 1.257 0.9999 1.0–295
MDZ Y = 36.365X − 16.163 0.9999 0.8–63