Impact of chrysosplenetin on the pharmacokinetics and anti-malarial efficacy of artemisinin against Plasmodium berghei as well as in vitro CYP450 enzymatic activities in rat liver microsome

Table 2 Standard curves equation of six probe substrates in inactive RLM

Probe substrates	Calibration curves	R value	Linear range (μM)
PN	Y = 9.486X + 0.3485	0.9999	0.5–111
CA	Y = 6.730X + 0.7809	0.9999	0.7–137
OPZ	Y = 4.148X + 2.1741	0.9999	0.5–141
DM	Y = 24.868X + 5.1424	0.9999	0.5–54
CLZ	Y = 20.918X + 1.257	0.9999	1.0–295
MDZ	Y = 36.365X − 16.163	0.9999	0.8–63

ISSN: 1475-2875