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Fig. 4 | Malaria Journal

Fig. 4

From: Associations between hepcidin and immune response in individuals with hyperbilirubinaemia and severe malaria due to Plasmodium vivax infection

Fig. 4

Associations between laboratory parameters, parasitaemia, hepcidin levels, and immune-related biomarkers. Statistically significant correlations between laboratory markers, parasitaemia, hepcidin levels, and immune-related biomarkers are shown for each study group. The correlations were assessed using the Spearman rank test. Green lines represent negative significant (p < 0.05) correlations and grey lines represent positive significant correlations. Icons for cytokines and chemokines are coloured according to their expression in the heat map shown in Fig. 2a. The other icons are coloured according to their expressions in the comparisons between study groups: grey icons are parameters with no difference between the two groups; blue and red icons represent downregulated and upregulated markers, respectively

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