Skip to main content
Fig. 2 | Malaria Journal

Fig. 2

From: Antibodies to Plasmodium falciparum merozoite surface protein-1p19 malaria vaccine candidate induce antibody-dependent respiratory burst in human neutrophils

Fig. 2

Naturally-acquired anti-PfMSP1p19 antibodies are major inducers of ADRB activity against P. falciparum merozoites. a ADRB chemiluminescence readout for 21 sera with high anti-PfMSP1p19 OD-ratios tested using either P. falciparum D10 merozoites (D10-PfM3′, black bars) or transgenic D10 merozoites in which the P. falciparum MSP1p19 gene was replaced by its P. chabaudi orthologue (D10-PcMEGF, black bars). D10-PfM3′ and D10-PcMEGF merozoites were tested in the same plate, with the same polymorphonuclear cells batch. b Boxplot graph showing the significant (P < 10−3) overall distribution of ADRB generated using sera and D10-PfM3′ or D10-PcMEGF transgenic merozoites. The median is indicated by a line, the 50 % percentiles indicated by the box limits and the upper and lower 25 % by whiskers

Back to article page