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Table 1 Antibody responses against MSP1p19 in Dielmo and Ndiop villagers tested for ADRB

From: Antibodies to Plasmodium falciparum merozoite surface protein-1p19 malaria vaccine candidate induce antibody-dependent respiratory burst in human neutrophils

Age groups (years)

N

Mean age (years)

Anti-PfMSP1p19 levelsa

% Positive respondersb

% High respondersb

ADRBc

DIELMO

 0–6

19

4.6

3.6 [1–9.1]

68

16

154 [46–354]

 7–14

31

10.9

3.5 [1–15]

48

13

231 [40–958]

 ≥15

69

37.4

9.2 [1–16.9]

87

62

380 [106–575]

 All

119

25.3

6.8 [1–16.9]

74

42

305 [40–958]

NDIOP

 0–14

49

8.8

6.4 [1–18.4]

80

37

162 [51–545]

 15–29

33

20.5

9.2 [1–19.7]

88

55

307 [113–1721]

 ≥30

32

43.9

11.9 [1–19.9]

94

69

370 [56–1147]

 All

114

21.8

8.8 [1–19.9]

86

51

262 [51–1721]

  1. aMean [range] antibody levels to PfMSP1p19 expressed in OD-ratio
  2. bPercent of responders (OD-ratio > 2) and of High responders (OD-ratio > 7)
  3. cMean level and range [min–max] of ADRB measured in villagers’ sera