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Table 1 Antibody responses against MSP1p19 in Dielmo and Ndiop villagers tested for ADRB

From: Antibodies to Plasmodium falciparum merozoite surface protein-1p19 malaria vaccine candidate induce antibody-dependent respiratory burst in human neutrophils

Age groups (years) N Mean age (years) Anti-PfMSP1p19 levelsa % Positive respondersb % High respondersb ADRBc
DIELMO
 0–6 19 4.6 3.6 [1–9.1] 68 16 154 [46–354]
 7–14 31 10.9 3.5 [1–15] 48 13 231 [40–958]
 ≥15 69 37.4 9.2 [1–16.9] 87 62 380 [106–575]
 All 119 25.3 6.8 [1–16.9] 74 42 305 [40–958]
NDIOP
 0–14 49 8.8 6.4 [1–18.4] 80 37 162 [51–545]
 15–29 33 20.5 9.2 [1–19.7] 88 55 307 [113–1721]
 ≥30 32 43.9 11.9 [1–19.9] 94 69 370 [56–1147]
 All 114 21.8 8.8 [1–19.9] 86 51 262 [51–1721]
  1. aMean [range] antibody levels to PfMSP1p19 expressed in OD-ratio
  2. bPercent of responders (OD-ratio > 2) and of High responders (OD-ratio > 7)
  3. cMean level and range [min–max] of ADRB measured in villagers’ sera