Table 1 Estimates of DNA sequence polymorphism and tests of neutrality at PvAMA-1 among Plasmodium vivax Korean isolates
Fragment | Segregating sites (S) | Singleton variable sites | Parsimony informative sites | Total no. of mutations | K | H | Hd ± SD | π ± SD | dN/dS | Tajima’s D | Fu and Li’s D | Fu and Li’s F |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
5ʹ-Terminal | 2 | 1 | 1 | 2 | 0.090 | 3 | 0.089 ± 0.048 | 0.00071 ± 0.00039 | 0 | −1.3151 (P > 0.10) | −1.2487 (P > 0.10) | −0.9681 (P > 0.10) |
Domain I | 35 | 10 | 25 | 35 | 4.856 | 20 | 0.830 ± 0.043 | 0.00786 ± 0.00087 | 0.765 | −1.1028 (P > 0.10) | −0.9845 (P > 0.10) | −0.6579 (P > 0.10) |
Domain II | 11 | 4 | 7 | 11 | 0.985 | 10 | 0.682 ± 0.038 | 0.00240 ± 0.00030 | 1.946 | −1.5941 (0.05 < P <0.1) | −1.4316 (P > 0.10) | −1.0111 (P > 0.10) |
Domain III | 11 | 3 | 8 | 11 | 1.839 | 12 | 0.848 ± 0.023 | 0.00601 ± 0.00054 | 0.433 | −0.5681 (P > 0.10) | −0.5407 (P > 0.10) | −0.3995 (P > 0.10) |
3ʹ-Terminal | 7 | 4 | 3 | 7 | 0.300 | 6 | 0.201 ± 0.066 | 0.00132 ± 0.00048 | 0.358 | −1.9993 (P < 0.05) | −2.3973 (P < 0.05) | −2.0530 (P < 0.05) |
Full | 66 | 22 | 44 | 66 | 8.070 | 30 | 0.961 ± 0.012 | 0.00478 ± 0.00038 | 0.703 | −1.4140 (P > 0.10) | −1.5383 (P > 0.10) | −1.2030 (P > 0.10) |