Table 3 Recovery times in surviving patients according to treatment group
From: Inhaled nitric oxide as adjunctive therapy for severe malaria: a randomized controlled trial
iNO (N = 80) (median, IQR) | Placebo (N = 83) (median, IQR) | HR (95 % CI) | p value | |
|---|---|---|---|---|
Time to discharge (days) | 4.0 (3.0–4.0) | 3.0 (3.0–4.0) | 1.1 (0.83–1.6) | 0.40 |
Time to eat (h) | 17 (7–37) | 10 (6–23) | 1.3 (0.92–1.7) | 0.15 |
Time to sit unsupported (h) | 41 (20–75) | 28 (13–60) | 1.3 (0.98–1.8) | 0.063 |
Time to localize pain (h) | 5 (0–11) | 2 (0–9.6) | 1.2 (0.84–1.6) | 0.38 |
Time to fever resolution (h) | 6 (0–31) | 6 (0–23) | 1.1 (0.78–1.4) | 0.73 |
Time to recovery of consciousness (h) | 14 (6–36) | 9 (4–19) | 1.2 (0.90–1.7) | 0.19 |
Time to 50 % parasite clearance (h) | 12 (9–16) | 12 (9–18) | 0.87 (0.63–1.2) | 0.37 |
Time to 90 % parasite clearance (h) | 19 (12–37) | 20 (14–37) | 0.85 (0.62–1.2) | 0.31 |
Time to parasite clearance (h) | 44 (35–63) | 44 (37–63) | 0.97 (0.71–1.3) | 0.83 |