Fig. 4

Seroprevalence curves for MSP-1 and AMA-1 antigens based on different immunoassays, fitted distributions, and seropositive cutoff determinations. The MSP-1p19 antigen was chosen to represent MSP-1 response as a whole. Curves represent ELISA (black lines) and multiplex assays (grey lines) with normal (solid lines) and lognormal (dashed lines) distributions. Seropositivity was based on mean + 3SD cutoff value for all comparisons. a Curves generated when using malaria-naive persons as reference. Note ELISA normal and lognormal seroprevalence curves for the MSP-1 antigen overlap. b Curves generated by finite mixture model approaches