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Table 1 Individual concentrations and deformability values that were normalized to DMSO or ddH2O control for respective anti-malarial drug treatments

From: Reduced deformability of parasitized red blood cells as a biomarker for anti-malarial drug efficacy

Drug name Concentration (≥4 × EC50) Median normalized deformability % Median increase in deformability P value
Chloroquine 1 µM 1.41 41 <0.0001
Mefloquine 1 µM 1.22 22 0.0002
Pyrimethamine 20 nM 1.80 80 <0.0001
Proguanil 100 µM 1.58 58 0.0052
Artesunate 10 nM 1.29 29 0.0022
Artemether 8 nM 1.95 95 <0.0001
Dihydroartemisinin 20 nM 2.11 111 <0.0001
Tetracycline 100 µM 0.93 −7 ns
Atovaquone 250 nM 1.46 46 0.0001
(+)-SJ733 1.08 µM 5.54 454 <0.0001
(−)-SJ733 1.08 µM 0.90 −10 ns
NITD246 3.6 nM 3.34 234 <0.0001