Table 1 Comparison between the parasite viability kinetic assay and the in vitro killing rate assay based on limiting dilutions using compounds from the Medicines for Malaria Venture Malaria Box
Compound | In vitro killing rate assay (standard assay) | Viability assay (fast assay) |
|---|---|---|
MMV000478 | Fast | Fast |
MMV665939 | Slow | Slow |
MMV019066 | Slow | Slow |
MMV019662 | Slow | Slow |
MMV007564 | Moderate | Fast/moderate |
MMV020750 | Moderate | Moderate |
MMV665789 | Moderate | Moderate |
MMV665928 | Fast | Fast |
MMV006767 | Moderate | Moderate |
MMV008149 | Slow | Slow |
MMV009108 | Slow | Slow |
MMV665924 | Fast | Fast |
MMV011895 | Fast | Fast |
MMV019017 | Fast | Fast |
MMV009063 | Fast | Fast |
MMV665794 | Moderate | Moderate |
MMV665824 | Slow | Slow |
MMV006455 | Fast | Fast |
MMV665852 | Moderate/fast | Fast |
MMV665888 | Moderate | Moderate |