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Table 2 Therapeutic index determination (MHC/MIC ratio)

From: New linear antiplasmodial peptides related to angiotensin II

 

MHC [M]

MIC [M]

MHC/MIC

Ang II

10−5

10−12

107

Peptide 5

10−5

10−14

109

Peptide 6

10−6

10−14

108

  1. Therapeutic index was determined for the compounds that had anti-plasmodial activity during the erythrocytic cycle of P. falciparum