Skip to main content

Table 2 Clinical trials of doxycycline monotherapy against P. falciparum malaria

From: Tetracyclines in malaria

Study demographic details

Regimen

Year

Place

References

Population

Nb

Dosage/d

Nb doses/d

Route

Nb days

Efficacy (%)

1971

USA

Clyde [107]

A

4

200 mg

2

PO

4

NR

1971

USA

Clyde [107]

A

9

200 mg

2

PO

7

NR

1981

West Malaysia

Ponnampalam [68]

C

9

4 mg/kg

NR

PO

4

44.4

1981

West Malaysia

Ponnampalam [68]

C

26

4 mg/kg

NR

PO

7

84.6

2001

Indonesia

Taylor [108]

A

20

200 mg

2

PO

7

64.7

  1. A adults, C children, NR not reported