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Table 3 Parasite clearance time (PCT)

From: Efficacy and safety of fixed dose combination of arterolane maleate and piperaquine phosphate dispersible tablets in paediatric patients with acute uncomplicated Plasmodium falciparum malaria: a phase II, multicentric, open-label study

Statistical summary

Age group 1 (6 months to <2 years)

Age group 2 (2 to <6 years)

Age group 3 (6 to ≤12 years)

 Censored

3 (13.6 %)

7 (14.3 %)

1 (1.4 %)

Summary (excluding censored values)

 n

19

42

69

 Mean ± SD

21.5 ± 6.33

21.0 ± 6.81

21.2 ± 5.58

 Min, max

12, 36

6, 31

12, 36

Time to parasite clearance (h)

 

 Quartile estimate (95 % confidence interval)

 

  25 %

18.0 (18.0, 20.0)

18.0 (13.0, 19.0)

18.0 (NE, NE)

  50 % (median)

22.0 (18.0, 24.0)

24.0 (19.0, 24.0)

23.0 (18.0, 24.0)

  75 %

30.0 (24.0, NE)

30.0 (24.0, 31.0)

24.0 (NE, NE)

  Mean

23. 5

22.4

21.5

  1. Overall the median PCT was estimated to be 24.0 h (18.0 to 24.0 h)